Department of Medical Laboratory Science

Faculty of Allied Health Sciences

Department of Medical Laboratory Science

Faculty of Allied Health Sciences

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Dr. R.P. Illeperuma


Official Address :

Department of Medical Laboratory Science,
Faculty of Allied Health Sciences,
University of Peradeniya,
Augusta Hill, Sri Amarawansa Mawatha
Peradeniya,
Sri Lanka


Email :

rpi@pdn.ac.lk

rpilleperuma@yahoo.com


Telephone :

+94 813999916

+94 777445101(Mobile)




Education Qualification

  • Ph.D (Yonsei University, Seoul, Korea )

  • MSD

  • BDS (Hons)

Professional Qualification / Teaching Experience

  • Senior Lecturer, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya.

  • Post-Doctoral Research Fellow- Oral Cancer Research Institute, Yonsei University, Seoul, Korea.

  • Visiting Lecturer at Postgraduate Institute of Medicine (PGIM), Colombo for Postgraduate Diploma in Family Medicine Course.

  • Visiting Lecturer at Institute of Indigenous Medicine (IIM), University of Colombo, Rajagiriya, Sri Lanka.

  • Assistant Teacher at the Department of Oral Pathology, Yonsei University College of Dentistry, Seoul, Korea (March 2008 –February 2012).

  • Lecturer In Western Medicine ( Modern Medicine Unit) Institute of Indigenous Medicine (IIM), University of Colombo, Rajagiriya, Sri Lanka Teaching General Pathology, Pharmacology, Physiology (2007-2012).

  • Registered General Dental Practitioner at Sri Lanka Medical Council.

  • General dental practice since March 2004.

  • Visiting Dental Surgeon at the Unilever Sri Lanka Limited, Colombo 14 (2005-2008).



Member & Awards

    Membership

  • Member of AACR (American Association for Cancer Research)
  • Member of IADR (International Association for Dental Research)
  • Member of IAOP (International Association of Oral Pathologists)
  • Member of SLDA (Sri Lanka Dental Association)


    • Awards

  • Full scholarship from Yonsei University, Seoul, Korea for PhD programme (2008-2012)

  • Award of Merit for the best research presentations- Annual research sessions, Yonsei University 2009. "Establishment of novel cell line for testing toxicity of Dental Materials using h-TERT transfected gingival fibroblasts".

  • Award of Merit for the best research presentations- Annual research sessions, Yonsei University 2010. "Cytokines might play a key role in carcinogenesis of oral submucous fibrosis"

  • Award of Merit for the best research presentations- Annual research sessions, Yonsei University 2011. "Impication of cytokines released from gingival fibroblasts exposed by Areca Nut extract in carcinogenesis".

  • The Best Presentation Award- For the oral presentation at 76th Annual sessions of Korean Academy of Oral and Maxillofacial Pathology (KAOMP), November 2011

  • IAOP Travel Award for at the 16th International Congress on Oral Pathology and Medicine, general sessions of the International Association of Oral Pathologists (IAOP). August 2012, Brazil. "Oxidative DNA damage in oral keratinocytes caused by cytokines released from fibroblasts by areca nut exposure".

  • NSF (National Science Foundation- Sri Lanka) Travel Award, August 2012 to participate 16th IAOP Congress in Sao Paulo, Brazil

  • Daphne Attygalle Prize for the Best Paper in Cancer, awarded by Sri Lanka Medical Association, November 2012. "A novel approach to understand carcinogenesis in oral submucous fibrosis"

  • Award of Merit for the commendable research presentations- FDI/CDA/SLDA joint International Conference & 80th Anniversary Annual scientific sessions of Sri Lanka Dental Association (SLDA) June 2013. "Fibroblasts are implicated in areca nutinduced carcinogenesis via oxidative DNA damage and nuclear aneuploidy"

Research Interests

  • Mechanisms of carcinogenesis in oral premalignant lesions
  • Carcinogenicity of Areca Nut
  • Testing antioxidants as a treatment modality in oral pre-cancer
  • Oral submucous fibrosis and Oral cancer
  • HPV involvement in Oral Cancer
  • HPV involvement in Oral Cancer
  • Herbal medicine in oraldiseases

Research Publication(Recent)

    Publications

  • Development of Brief Image Quality Evaluation Criteria for DigitalOrthoPantomography (OPG) Images in Dental Radiography. AMC Kumarihami, SDL Heshani, P Sathyathas, RP Illeperuma Journal of Health Science2018,6, 139-147
  • Effect of Areca nut on Helicobacter pylori-induced gastric diseases in mice.Lee J, Gunawardhana ND, Jang S, Choi YH, Illeperuma RP, Kim A, Su H, Hong YA, Kim JH,Kim J, Jung DW, Cha IH, Bak EJ, Cha JH. J Microbiol Biotechnol. 2016 Oct 28;26(10):1817-1823
  • Identification of a combined biomarker for malignant transformation in oral submucous fibrosis. Bazarsad S, Zhang X, Kim KY, Illeperuma R, Jayasinghe RD, Tilakaratne WM, Kim J. J Oral Pathol Med. 2016 Aug 6. doi: 10.1111/jop.12483.
  • Demographic and Histopathological Differences of Oral Squamous Cell Carcinoma; Analysis of 4394 Cases from Sri Lanka. Siriwardena BSMS, Jayathilake DSY, Pitakotuwage TN, Illeperuma RP, Kumarasiri PVR , Attygalla AM, Peiris HRD, Tilakaratne WM. J Clin Exp Oncol 2015, 4:4.
  • Areca nut exposure increases secretion of tumor-promoting cytokines in gingival fibroblasts that trigger DNA damage in oral keratinocytes. Rasika P. Illeperuma, Do Kyeong Kim, Young Jin Park, Hwa Kyung Son, Jue Young Kim, Jinmi Kim, Doo Young Lee, Ki-Yeol Kim, Da-Woon Jung, Wanninayake M. Tilakaratne, Jin Kim. Int J Cancer. 2015 Dec 1;137(11):2545-57.
  • A Distinct Role for Interleukin-6 as a Major Mediator of Cellular Adjustment to an Altered Culture Condition.Son HK, Park I, Kim JY, Kim do K, Illeperuma RP, Bae JY, Lee DY, Oh ES, Jung DW, Williams DR, Kim J. J Cell Biochem. 2015Nov;116(11):2552-62.

  • Cytotoxicity evaluation of zinc oxide-eugenol and non-eugenol cements using different fibroblast cell lines. Kwon JS, Illeperuma RP, Kim J, Kim KM, Kim KN.Acta Odontol Scand. 2013 May 21.

  • Immortalized gingival fibroblasts as a cytotoxicity test model for dental materials. Illeperuma RP, Park YJ, Kim JM, Bae JY, Che ZM, Son HK, Han MR, Kim KM, Kim J. J Mater Sci Mater Med. 2012 Mar;23(3):753-62.

  • Relationship of fibrosis and the expression of TGF-β1, MMP-1, and TIMP-1 with epithelial dysplasia in oral submucous fibrosis. Rasika Pawiththra Illeperuma, Mi Heon Ryu, Ki Yeol Kim, Wanninayake Mudiyanselage Tilakaratne, Jin Kim. Oral Med Pathol 15 (2010) 21

  • Role of TGF beta-1, MMP-1, TIMP-1 and PCNA in pathogenesis and malignanat transformation of oral submucous fibrosis Illeperuma RP, M.H. Ryu, K.Y.Kim, J. Kim and W.M Tilakaratne. Proceedings of the University of Peradeniya Annual Research Sessions 2009, vol. 14: 102-104



    • Research Presentations (International)

  • BMC Rathnayake, RPIlleperuma, U Ralapanawa,TA Jayalath, NS Gunarathna(2019).A study on prevalence of ischemic heart diseases among hypertensive patients participating at a hypertension clinic, Teaching hospital, Peradeniya In: proceedings of the Peradeniya University International Research Sessions; 11th&12thSeptember2019 ; Kandy, Peradeniya: iPURSE; 2019. Abstract no 081
  • R.P.Illeperuma, W.M.K. M. Bandara, R. M. A.P. Ramanayake,S. Kodithuwakku, R. D. Jayasinghe, W. M. Tilakaratne. (2019).Expression of oxidative stress responsive genes in oral cancers and oral potentially malignant disorders with the history of areca-nut consumption. 9thAnnual conference of The Asian Society of Oral and Maxillofacial Pathology (ASOMP). 22ndto 24thAugust2019 at Mahsa University, Kuala Lumpur, Malaysia.
  • T.S. Amarasinghe, R.P. Illeperuma, N. Seki and T. Sumiyoshi. (2019).Mental and Physical Health Status of the School Children in Niigata Prefecture-Japan: A Preliminary Study.InBook of AbstractsSeventh Conference on Sri Lanka-Japan Collaborative Research. 24thAugust2019, University of Peradeniya, Sri Lanka.
  • Gunasekara PSP, Illeperuma RP, Kodithuwakku SP. (2019). Arica Nut water extract induces the DNA Damage in Oral Fibroblasts and increases the metastasis potential in oral carcinoma cells in vitro. Proceedings of the 5thFaculty of Agriculture Undergraduate Research Symposium held in Faculty of Agriculture, University of Peradeniya, Peradeniya, Sri Lanka, 21stFebruary2019pp 76
  • Prasadani YGM,Kodithuwakku SP,Illeperuma RP. (2019). in vitroAnti-cancer potency of Osbeckia octandraL. (Heen Bovitiya) leave extract on carcinoma cells.Proceedings of the 5thFaculty of Agriculture Undergraduate Research Symposium held in Faculty of Agriculture, University of Peradeniya, Peradeniya, Sri Lanka, 21stFebruary2019pp 113
  • R Illeperuma, MK Bandara, DK Kim, S Siriwardena, R Jayasinghe, J Kim. (2019).Antioxidant rich tropical herbs to combat areca-nut induced OPMDs. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 128 (1), e80-e81https://doi.org/10.1016/j.oooo.2019.02.203.In: proceeding of the 72ndAAOMP conference; 23rd-28thJune2018 ; Vancouver, Vancouver: AAOMP; 2018. (Page 181)
  • T.S.Amarasinghe, N.Seki, T. Sumiyoshi,R.P.Illeperuma. (2018). Students’ life style mental and physical health inheavy snowing rural area: comparison with cross-sectional survey conducted fifteen years ago. Proceedings of the InternationalNursing Congress 2018 organized by the Facultyof Allied health Science, University of Peradeniya, 6th&7thApril 2018 at Hotel Oakray Regency, Peradeniya, Sri Lanka.
  • Lokuruge SK, Dissanayake BN, Illeperuma RP, Pinto V, Gamage CD.(2018).Central line associated bloodstream infections and colonization in an intensive care unit of a tertiary care hospital. Inproceedings of the Kandy Society of Medicine; 40th AnnualAcademic Sessions 15th-17thFebruary2018; Kandy. Abstract no OP18.
  • Dahanayake SD, Hunukumbura RMCB, Illeperuma RP. (2017) Knowledge and attitudes on infertility among couples attending to infertility clinic at Castle street hospital for women, Colombo. In: proceedings of National Health Research Symposium 2017; 4th&5thDecember2017 BMICH, Colombo. Abstract no 341 page 345
  • Baddevithana AK, Illeperuma RP, Jayasinghe RD, Siriwardena BSMS, Tilakaratne WM.(2017).Human Papiloma Virus infection and its correlation withexpression of p16 gene in oral potentially malignant disorders and oral cancer. In: proceedings of the Peradeniya University International Research Sessions; 24thNovember 2017; Kandy, Peradeniya: iPURSE; 2017. Abstract no 341
  • Bandara WMKM, Baddevithana AK, FernandoPS, Siriwardana BSMS, JayasingheRD, TilakaratneWM, Illeperuma RP.(2017).Effects of antioxidant rich-Sri Lankan herb “Schumacheria castaneifolia” extract on Areca-Nut induced DNA damage in mice. 8thAnnual conference of The Asian Society of Oral and Maxillofacial Pathology (ASOMP). 19th& 20thAugust2017, Vijayawada, India.
  • Baddevithana AK, Jayasinghe RD, Siriwardena BSMS, Tilakaratne WM,Illeperuma RP.(2017)Expression of p16 gene and HPV oncogene inoral potentially malignant disorders and oral cancer: A preliminary study. E-Poster presentation at the 8thAnnual conference of The Asian Society of Oral and Maxillofacial Pathology (ASOMP). 19th& 20thAugust2017, Vijayawada, India. (Award for best presentation)
  • Weerasingha BRGTK, Hilmi AJ, Illeperuma RP.(2017).The effect of music on the reduction of cancer-related pain. Annual Scientific Sessions of the Sri Lanka Dental Association-Kandy Branch 2017; 21st&22ndJanuary 2017 Kandy
  • Kumarihami AMC, Heshani SDL, Sathya P, Illeperuma RP.(2017)Development of brief image quality evaluation criteria for digital orthopantomography (OPG) images in dental radiography. Annual Scientific Sessions of the Sri Lanka Dental Association-Kandy Branch 2017; 21st&22ndJanuary 2017 Kandy
  • Bandara WMKM, Do KK, Jayasinghe RD, Siriwardene BSMS, Tilakeratne WM, Jin K, Illeperuma RP.(2016).Expression of ɤ–h2ax and p53 in oral cancer and oral potential malignant disorders with areca nut history. InProceedings of the Peradeniya University International Research Sessions; 4th&5thNovember 2016; Kandy, Peradeniya: iPURSE; 2016. Abstract no 414
  • Jayawardena JACK, Tamara R, Jayasooriya PR, Illeperuma RP.(2016)Learning experience of medical laboratory students towards a self-study E-Learning resource: a preliminary study. InProceedings of the Peradeniya University International Research Sessions; 4th&5thNovember 2016; Kandy, Peradeniya: iPURSE; 2016. Abstract no 211
  • Amarakoon D, RJK Seneviratne, R.P.Illeperuma.(2016).Comparison of wound healing potential of papaya peel dressing with povidone-iodine dressing on diabetic foot ulcers. InProceedings of the Peradeniya University International Research Sessions; 4th&5thNovember 2016, Peradeniya: iPURSE; 2016. Abstract no 69
  • Baddevithana AK, Illeperuma RP, Jayasinghe RD, Siriwardena BSMS, Tilakaratne WM.(2016).Expression of p16 gene in oral potentially malignant disorders and oral cancer: a preliminary study. InProceedings of the Peradeniya University International Research Sessions; 4th&5thNovember 2016; Kandy, Peradeniya: iPURSE; 2016. Abstract no 533
  • Bandara WMKM, Illeperuma RP, Do KK, Jayasinghe RD, Siriwardene BSMS, Tilakeratne WM, Jin K.(2016).Areca-Nut Induced DNA Damage Can Be Reversed By Shumacheria Castaneifolia. 18thInternationalCongress on Oral Pathology and Medicine, general sessions of the International Association of Oral Pathologists (IAOP) 8th-11thSeptember; Chennai: IAOP; 2016. Abstract no 199
  • BandaraWMKM, Illeperuma RP, Do KK, Jayasinghe RD, Siriwardene BSMS, Tilakeratne WM, Jin K. (2016).Testing efficacy of antioxidant rich herbal extract in reducing arecanut induced carcinogenesis. InProceedings of the 129thAnniversaryInternational Medical Congress Sri Lanka Medical Association; 27thJuly 2016; Colombo: SLMA; 2016. Abstract no 296
  • W.M.K.M Bandara, N.Fujiwara and R.P.Illeperuma(2015). Effects of acute high glucose and osmolality on changes of intracellular calcium level in mouse neocortical slices. Peradeniya University International Research Sessions. 5th&6thNovember 2015, Peradeniya, Sri Lanka proceedings of the Perdeniya University International Research Sessions; iPURSE; 2015. Abstract no 57
  • Sirajudeen M.A.A, Nageeb B.M, Illeperuma R.P, Thajudeen, I.H. (2015). A comparative clinical study of the Unani compound medical preparation for Antilipidaemic activity with special reference to the modern drug Atorvastatin. Proceedings of the Annual Research Symposium, University of Colombo, 25thOctober 2015. (http://archive.cmb.ac.lk:8080/research/handle/70130/4211)
  • WMKM Bandara, RP Illeperuma, D K Kim, BSMS Siriwardena, RD Jayasinghe, WM Tilakaratne, Jin Kim.(2015).Analysis of DNA double strand damage during oral carcinogenesis in Areca Nut chewers. International Symposium of Oral Cancer and Cancer Prevention. 1stOctober 2015, Yonsei University, Seoul, South Korea.
  • Shadavlonjid Bazarsad, Xianglan Zhang, Ki-Yeol Kim, Rasika P Illeperuma, Wanninayake M Tilakaratne, Jin Kim.(2015).Prediction model for risk assessment via combined biomarkers in oral submucous fibrosis. International Symposium of Oral Cancer and Cancer Prevention. 1stOctober2015, Yonsei University, Seoul, SouthKorea
  • Dharmapala AD, Siriweera EH, Karunathilake NP, Illeperuma RP, Kumarasiri PVR, Samarasinghe AKBBTB, Kotakadeniya HMSRB, Galketiya KB.(2015).Human Papilloma Virus (HPV) infection and oesophageal cancer in Sri Lanka. In: proceedings of the Kandy Society of Medicine; 37thAnnualAcademic Sessions 11th–14th2015; Kandy. Abstract no OP06 Page49.
  • Kim DK, Illeperuma RP, Tilakaratne WM, Kim J.(2014).Antioxidant prevents areca nut-induced carcinogenesis by inhibiting IL-6. International Congress onOral Cancer Smokeless Tobacco and Arecanut. 8th&9thAugust 2014, Kandy, Sri Lanka
  • R.P.Illeperuma, D. K. Kim, Y. J. Park, J. Y. Kim, W. M. Tilakaratne, J. Kim.(2014).Elucidating mechanisms inducing oxidative stress by areca nut in oral mucosa. Peradeniya University International Research Sessions iPURSE; 4th&5thJuly 2014, Peradeniya, Sri Lanka
  • Y.R.I.A Gunarathna, R.P.Illeperuma, S.Hirano.(2014).The morphogenesis patterns of the optic cup development in the chick embryo. Peradeniya University International Research SessionsiPURSE;4th&5thJuly 2014, Peradeniya, Sri Lanka
  • R.P.Illeperuma, B S M S Siriwardena, D S Y Jayathilake, T N Pitakotuwage, P V R Kumarasiri, A M Attygala, R D Peiris, W M Tilakaratne.(2014). Analysis of oral cancer cases of Sri Lanka for 13 years. 17thInternationalCongress on Oral Pathology and Medicine, General Sessions of the International Association ofOral Pathologists (IAOP). 25th–30thMay2014 in Istanbul, Turkey. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 119(3):e163–e164, MAR 2015 DOI: 10.1016/j.oooo.2014.07.271, Issn Print: 2212-4403
  • R.P.Illeperuma, B S M S Siriwardena, D S Y Jayathilake, T N Pitakotuwage, P V R Kumarasiri, A M Attygala, R D Peiris, W M Tilakaratne.(2014).A retrospective study analyzing 4394 oral cancer cases in Sri Lanka. Oral presentation at the 6thAnnual Meeting of Asian Society of Oral and Maxillofacial Pathology (ASOMP). 22ndFebruary 2014 in HICC-Novotel, Hyderabad, India.
  • BSMS Siriwardena, RP Illeperuma, DSY Jayathilake, TN Pitakotuwage, PVR Kumarasiri, AM Attygala, RD Peiris, WM Tilakaratne.(2013)Analysis of demographic data of 4394 cases of oral squamous cell carcinoma. Sri Lanka Associationof Oral and MaxillofacialSurgeons(SLAOMS)10thannual Scientific Sessions 27thJuly 2013 at Hotel Amaya Hills, Kandy, Sri Lanka(Wining 1stPlace)
  • RP Illeperuma, HMSC Dissanayake, YJ Park, H K Son, DW Jung, W M. Tilakaratne, J Kim.(2013).Fibroblasts are implicated in areca nut-induced carcinogenesis via oxidative DNA damage and nuclear aneuploidy. FDI/CDA/SLDA joint International Conference & 80thAnniversary Annual scientific sessions of Sri Lanka Dental Association (SLDA). 28th-30th June 2013, BMICH, Colombo, Sri Lanka.

  • Illeperuma RP, Park YJ, Son HK, Jung DW, Tilakaratne WM, Kim J. Oxidative DNA damage in oral keratinocytes caused by cytokines released from fibroblasts by areca nut exposure. Oral presentation at the 16th International Congress on Oral Pathology and Medicine, general sessions of the International Association of Oral Pathologists (IAOP). July 30th – August 4th 2012 in Sao Pedro, Sao Paulo, Brazil. ( Recipient of IAOP Travel Award and NSF Travel Grant)

  • Rasika P Illeperuma, Young Jin Park, Hwa Kyung Son, Jinmi Kim, Da-Woon Jung, W.M Tilakaratne, Jin Kim. Implication of cytokines released from gingival fibroblasts exposed by Areca Nut extract in carcinogenesis. Poster presentation at the annual meeting of the American Association for Cancer Research (AACR). March 31 –April 4th 2012 in Chicago, IL, USA.

  • Rasika P Illeperuma, Young Jin Park, Hwa Kyung Son, Jinmi Kim, Da-Woon Jung, W.M Tilakaratne, Jin Kim. Implication of cytokines released from gingival fibroblasts exposed by Areca Nut extract in carcinogenesis. Poster presentation at the 11th Yonsei Dental International Symposium (Award of Merit for best research presentations). December (3rd) 2011 in Seoul, South Korea.

  • H.K Son, I.Park, R.P.Illeperuma, J.Y Kim, J.Kim. Modulation of epithelial differentiation by different media in HPV16 E6/E7-immortalized human oral keratinocytes. Poster presentation at the 11th Yonsei Dental International Symposium (Award of Merit for best research presentations). December (3rd) 2011 in Seoul, South Korea.

  • Rasika P Illeperuma, Young Jin Park, Hwa Kyung Son, Jinmi Kim, Da-Woon Jung, W.M Tilakaratne, Jin Kim. Implication of cytokines released from gingival fibroblasts exposed by Areca Nut extract in carcinogenesis. Oral presentation at the 76th meeting of Korean Academy of Oral and Maxillofacial Pathology. (Best presentation Award). November (25-26th) 2011 in Seoul, South Korea.

  • H.K Son, I.Park, R.P.Illeperuma, J.Y Kim, J.Kim. Modulation of epithelial differentiation by different media in HPV16 E6/E7-immortalized human oral keratinocytes. Oral presentation at the 76th meeting of Korean Academy of Oral and Maxillofacial Pathology. November (25-26th) 2011 in Seoul, South Korea.

  • Rasika P Illeperuma, Young J Park, Jin M Kim, Da W Jung, Wanninayake M Tilakaratne, Jin Kim. Investigating the carcinogenesis of oral submucous fibrosis, with special reference to the role of cytokines released from submucosal fibroblasts. Oral presentation at Annual conference of Australian and New Zealand Association of Oral and Maxillofacial Surgeons Conference OMAX2011. October (13-15th) 2011 in Melbourne, Australia.

  • Rasika P Illeperuma, Young Jin Park, Hwa Kyung Son, Jinmi Kim, Da-Woon Jung, W.M Tilakaratne, Jin Kim. Utilization of hTERT immortalized gingival fibroblasts in an in vitro model to elucidate cytokine secretion of submucosal fibroblasts in oral submucous fibrosis. Poster presentation at the 75th meeting of Korean Academy of Oral and Maxillofacial Pathology. June (3-4th) 2011 in Pusan, South Korea

  • Rasika P Illeperuma, Young Jin Park, Jinmi Kim, Da-Woon Jung, W.M Tilakaratne, Jin Kim. Cytokines might play a key role in carcinogenesis of oral submucous fibrosis. Poster presentation at the 10th Yonsei Dental International Symposium (Award of Merit for best research presentations). November (19th) 2011 in Seoul, South Korea.

  • Rasika P Illeperuma, Young Jin Park, Jinmi Kim, Da-Woon Jung, W.M Tilakaratne, Jin Kim. Cytokine expression by the treatment of areca nut extract in cultured fibroblasts: Comparison between normal oral fibroblasts and hTERT-transfected fibroblasts. Oral presentation at the 15th International Congress on Oral Pathology and Medicine, general sessions of the International Association of Oral Pathologists (IAOP). August (16-20th) 2010 in Seoul, Korea.

  • Sook Moon, Rasika P Illeperuma, Yong Jin Park, Jin Kim. Usefulness of hTERTtransfected gingival fibroblasts in oral cancer research. Poster presentation at the 15th International Congress on Oral Pathology and Medicine, general sessions of the International Association of Oral Pathologists (IAOP). August (16-20th) 2010 in Seoul, Korea

  • R.P.Illeperuma, Y.J Park, J.M. Kim, Z.M. Che, M.R. Han, K.M. Kim, J. Kim Immortalized gingival fibroblasts for a cytotoxicity test model of dental materials. Oral presentation at the 88th general sessions of the International Association for Dental Research (IADR). July (14-17th) 2010 in Barcelona, Spain.

  • Rasika P Illeperuma, Young Jin Park, Jinmi Kim, Zhong Min Che, and Jin Kim. Establishment of a cell line of hTERT transfected human gingival fibroblsts. Poster presentation at Korean Basic dental science Annual Conference. November (27-28th) 2009 in Seoul, South Korea.

  • Rasika P Illeperuma, Mi Heon Ryu, Ki Yeol Kim, W M Tilakaratne, Jin Kim. Influence of fibrosis and extracellular matrix remodeling in Oral Submucous Fibrosis on carcinogenesis: Immunohistochemical evaluation using Sri Lankan biopsy tissues. Oral presentation at the 4th meeting of Asian Society of Oral and Maxillofacial Pathologists (ASOMP). November (6-7th) 2009 in Beijing, China.

  • Rasika P Illeperuma, Young Jin Park, Jinmi Kim, Zhong Min Che, and Jin Kim. Establishment of a novel cell line for testing toxicity of Dental Materials using h-TERT transfected gingival fibroblasts. Poster presentation at the 9th Yonsei Dental International Symposium (Award of Merit for best research presentations). October (31st) 2009 in Seoul, South Korea.

  • Rasika P Illeperuma, Mi Heon Ryu, Ki Yeol Kim, W M Tilakaratne, Jin Kim. Effects of fibrosis and extracellular matrix remodeling in oral submucous fibrosis on its malignant transformation of the epithelium: Immunohistochemical evaluation by testing expressions of TGF beta-1, MMP-1, TIMP-1, and PCNA index. Poster presentation at the 71st meeting of Korean Academy of Oral and Maxillofacial Pathology. May (22nd) 2009 in Seoul, South Korea.

  • Rasika P Illeperuma, Mi Heon Ryu, Ki Yeol Kim, W M Tilakaratne, Jin Kim. Evaluation of PCNA index and expressions of TGF β-1, MMP-1, and TIMP-1 in oral submucous fibrosis. Poster presentation at Korean Basic dental science Annual Conference. December (2-3rd) 2008 in Seoul, South Korea.


    • Research Presentations (Local)

  • RP Illeperuma, HMSC Dissanayake, YJ Park, H K Son, DW Jung, W M. Tilakaratne, J Kim. Fibroblasts are implicated in areca nut-induced carcinogenesis via oxidative DNA damage and nuclear aneuploidy. FDI/CDA/SLDA joint International Conference & 80th Anniversary Annual scientific sessions of Sri Lanka Dental Association (SLDA). June 28th -30th 2013, BMICH, Colombo, Sri Lanka.

  • RP Illeperuma, YJ Park, WM Tilakaratne, J Kim. A Novel approach to understand carcinogenesis in oral submucous fibrosis. Sri Lanka Medical Association 125th Anniversary International Medical congress. July 2nd -6th 2012, BMICH, Coombo, Sri Lanka.

  • R.P. Illeperuma, M.H. Ryu, K.Y.Kim, J. Kim and W.M Tilakaratne. Role of TGF beta- 1, MMP-1, TIMP-1 and PCNA in pathogenesis and malignanat transformation of oral submucous fibrosis. Peradeniya University research sessions December 2009, Peradeniya, Sri Lanka.



Curriculum Vitae




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